|
KMID : 1037420060010010017
|
|
Journal of Korean Skull Base Society
2006 Volume.1 No. 1 p.17 ~ p.23
|
|
|
Treatment Results of Inflammatory Pseudotumor Involving the Skull Base
|
|
Cho Yang-Sun
Lee Dong-Kyung
So Yoon-Kyoung
Hong Sung-Hwa
Chung Won-Ho
Park Kye-Hoon
|
|
|
Abstract
|
|
|
|
This study was performed to evaluate the response to steroid and radiation therapy in inflammatory pseudotumors (IPT) involving the skull base. Eight patients with inflammatory pseudotumor of the skull base were retrospectively evaluated. Of these, six patients were diabetic. All patients underwent an initial high dose of steroid therapy. Seven out of eight patients underwent subsequent low doses of steroid maintenance. Additional low dose radiation therapy was performed on six patients. We reviewed the medical records and radiological findings of the patients to evaluate their responses to the steroid and radiation therapy. In all patients, the initial response to steroid therapy was satisfactory. However, seven patients showed recurring symptoms after the cessation of steroid therapy. In five out of six patients, low dose radiation therapy resulted in recurrences. On follow-up MR imaging, none of the patients showed complete remissions of the disease. This observation demonstrates aggressive clinical characteristics of IPT involving the skull base and its poor response to steroid therapy and low dose radiation therapy. For improving control, more aggressive initial efforts including high dose radiation therapy with or without concurrent steroid therapy may play a causative role.
|
|
|
KEYWORD
|
|
|
Pseudotumor, Skull base, Corticosteroids, Radiation
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|